Journal of Materials Science and Engineering with Advanced TechnologyAuthor's: Hamid Reza Janghorban
Pages: [21] - [37]
Received Date: January 28, 2017; Revised February 23, 2017
Submitted by:
DOI: http://dx.doi.org/10.18642/jmseat_7100121770
One of the significant challenges in designing an ideal cage is the
mechanical modulus mismatch between the implant and surrounding host
tissue which results in stress shielding. In this study, a
nano-hydroxyapatite/polyamide 66 (n-HA/PA66) composite with mechanical
properties close to spongy bone to be designed and characterized as an
intervertebral fusion cage to perform spinal fusion between vertebrae
in the lumbar spine. A pure natural nano-hydroxyapatite (n-HA) powder
was prepared by annealing bovine bone at 1000°C followed by 10h
mechanical alloying. The nano-hydroxyapaptite/ polyamide 66 and
polyamide 66 (PA66) cage were prepared by injection method. X-ray
diffraction (XRD), scanning electron microscopy (SEM), and energy
dispersive spectrophotometer (EDS) were used to characterize the
powder and composites samples. The results showed that addition of
nano-hydroxyapaptite results in the
improvement of both mechanical and bioactivity properties. The optimum
n-HA/PA66 exhibited the compressive strength and elastic modulus of
46.98 ± 2MPa and 1.53 ± 0.3GPa, respectively, which is close to
spongy bone. In addition, observation of the superior apatite
formation ability of n-HA/PA66 compared to PA66 indicates that it can
be used as a bone replacement material.
cage, polyamide, hydroxyapatite, back pain.
