Author's: N. Y. ABOU-ZIED, A. I. WALY, N. G. KANDILE, A. A. RUSHDY, MANAL A. EL-SHEIKH and H. M. IBRAHIM
Pages: [93] - [123]
Received Date: November 10, 2012
Submitted by:
Modification of chitosan (CS) using monochloroacetic acid in the
presence of sodium hydroxide under different reaction conditions were
studied to determine the optimum conditions for preparing the
O-carboxymethylchitosan (O-CMCS). The prepared O-CMCS was
characterized by its nitrogen content, degree of substitution and its
solubility in different solvent or water under different pH values.
Evaluation of the antibacterial activity of CS and O-CMCS expressed in
MIC and MBC against E. coli as Gram (–ve) bacteria and S.
aureus as Gram (+ve) bacteria via broth tube dilution method was
investigated.
O-CMCS /viscose blended films were prepared by mixing O-CMCS and
viscose in water as co-solvent, and regenerated in coagulation bath
mentioned in the experimental part. The obtained O-CMCS/viscose
blended films were characterized via its nitrogen content, tensile
strength, elongation at break, Fourier transform infrared spectroscopy
(FT-IR), and thermal gravimetric analysis (TGA). Evaluation of the
antibacterial activity of the O-CMCS /viscose blended films, against
Gram (–ve) bacteria and Gram (+ve) bacteria was measured via both
disk diffusion method and bacterial count methods. These blended films
show good antibacterial effects towards both Gram (+ve) and Gram
(–ve) bacteria. The antibacterial activity of the blended films
increased and the tensile strength decrease as the O-CMCS percent
increase in the blended film.
cellulose xanthate, viscose, carboxymethylchitosan, polymer blend film, antibacterial properties.